Skip to main content
Home / Calculators / PT-141
Sexual HealthFDA Category 1 - Feb 2026No login required

PT-141 Reconstitution & Dosage Calculator

FDA-approved melanocortin receptor agonist (Vyleesi) for hypoactive sexual desire disorder. Used off-label in both sexes. Onset: 45–90 minutes.

Half-life: 120 minFrequency: As needed (max 1x per 72 hours)Route: Subcutaneous

PT-141 Reconstitution Calculator

Pre-filled with standard PT-141 values. Adjust as needed.

Typical range: 1–2mg per use
RECONSTITUTION PROCESS
BAC H2O10mg1. DRAW 2mL BAC2. INJECT INTO VIAL3. SWIRL TO DISSOLVE4. DRAW 0.20mL DOSE
10mg + 2mL → 5000 mcg/mL
Concentration5000 mcg/mL
Draw volume0.200 mL
Draw to (100-unit syringe)20.0 units
Total doses per vial10 doses
Save this calculation to your dashboard
Create free account →

PT-141 Dosing Guide

Standard: 1–2mg subcutaneously 45–90 min before sexual activity. Maximum once every 72 hours. Duration: up to 12 hours. Start with 1mg to assess tolerance.

Blood markers to track

Blood pressure (PT-141 may temporarily elevate)TestosteroneEstradiol

Note: FDA-approved as Vyleesi. Common effects: flushing, nausea, headache. Monitor BP. Avoid with cardiovascular disease.

WHAT TO DO NEXT

You have the dose. Now track whether it’s doing anything.

Log every PT-141 injection alongside your Blood pressure (PT-141 may temporarily elevate)and Testosterone readings. Compare draws over time in your free dashboard — so the next change you make is based on your numbers, not a guess.

Start tracking PT-141 free →

No credit card · Free forever tier

PT-141 protocol guides

PT-141 Protocol: Dosing & Timing

Read guide →

Testosterone Optimization Guide

Read guide →

Peptide Injection Guide for Beginners

Read guide →
FREE COMPANION GUIDE
You know your PT-141 dose. Know the labs it moves.
Get the free Peptide Blood Work Checklist - the exact biomarkers to baseline and monitor when running PT-141, with research-grade reference ranges.
No spam. Unsubscribe in one click. Just the checklist.
PDF
40+
biomarkers
per protocol
← View all 16 peptide calculators

NOT MEDICAL ADVICE. FOR INFORMATIONAL USE ONLY. CONSULT A LICENSED HEALTHCARE PROVIDER. · All Calculators · Blog · Home