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Semax Reconstitution & Dosage Calculator

Synthetic heptapeptide derived from the ACTH 4-10 fragment. Studied in Russia for cognitive enhancement, neuroprotection, and stroke recovery.

Half-life: ~minutes (intranasal)Frequency: 1–2x dailyRoute: Intranasal (most common) or subcutaneous

Semax Reconstitution Calculator

Pre-filled with standard Semax values. Adjust as needed.

Typical range: 300–600mcg per dose
RECONSTITUTION PROCESS
BAC H2O5mg1. DRAW 2mL BAC2. INJECT INTO VIAL3. SWIRL TO DISSOLVE4. DRAW 0.16mL DOSE
5mg + 2mL → 2500 mcg/mL
Concentration2500 mcg/mL
Draw volume0.160 mL
Draw to (100-unit syringe)16.0 units
Total doses per vial12 doses
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Semax Dosing Guide

Standard intranasal: 300–600mcg per dose, 1–2x daily. Cycled 2–6 weeks. Russian clinical protocols for stroke recovery use much higher doses (4–9mg/day) but optimization use stays at the lower end.

Blood markers to track

BDNF (specialized)CortisolCBC

Note: Russian clinical peptide. Not FDA-approved. Upregulates BDNF + NGF. Stacks commonly with Selank for combined cognitive-mood support. Short nasal half-life means frequent dosing for sustained effect.

Frequently Asked Questions

What is the standard Semax dose?

Standard intranasal: 300–600mcg per dose, 1–2x daily. Cycled 2–6 weeks. Russian clinical protocols for stroke recovery use much higher doses (4–9mg/day) but optimization use stays at the lower end.

How do I reconstitute Semax?

Add 2mL of bacteriostatic water to a 5mg vial of Semax to get a concentration of 2500 mcg/mL. This gives 400mcg per 16 units on a 100-unit insulin syringe.

What blood markers should I track while running Semax?

Common biomarkers tracked alongside Semax protocols include BDNF (specialized), Cortisol, CBC. Establishing a baseline panel before starting and re-drawing labs at consistent intervals lets you measure changes against your own reference point, generic lab ranges are less informative than your personal trend over time. MyProtocolStack tracks each of these biomarkers in the context of your active Semax protocol.

Last reviewed: June 2026. For education and tracking only, not medical advice. Confirm any dose with a licensed healthcare provider.

WHAT TO DO NEXT

You have the dose. Now track whether it’s doing anything.

Log every Semax injection alongside your BDNF (specialized)and Cortisol readings. Compare draws over time in your free dashboard, so the next change you make is based on your numbers, not a guess.

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Related Cognitive peptide calculators

Selank

250–500mcg per dose

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Dihexa

8–45mg daily

Open calculator →
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NOT MEDICAL ADVICE. FOR INFORMATIONAL USE ONLY. CONSULT A LICENSED HEALTHCARE PROVIDER. · All Calculators · Blog · Home