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Retatrutide Reconstitution & Dosage Calculator

Triple agonist (GLP-1 / GIP / glucagon) showing ~24% mean body weight reduction at 48 weeks in Phase 2 trials - the largest weight-loss effect of any GLP-1 class compound to date.

Half-life: ~6 daysFrequency: Once weeklyRoute: Subcutaneous

Retatrutide Reconstitution Calculator

Pre-filled with standard Retatrutide values. Adjust as needed.

Typical range: 1–12mg weekly (titration)
RECONSTITUTION PROCESS
BAC H2O12mg1. DRAW 2mL BAC2. INJECT INTO VIAL3. SWIRL TO DISSOLVE4. DRAW 0.33mL DOSE
12mg + 2mL → 6000 mcg/mL
Concentration6000 mcg/mL
Draw volume0.333 mL
Draw to (100-unit syringe)33.3 units
Total doses per vial6 doses
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Retatrutide Dosing Chart in Units

Convert Retatrutide mg dose to insulin syringe units across common compounded concentrations. Use the calculator above for non-standard concentrations.

Dose (mg)2.5 mg/mL conc.5 mg/mL conc.10 mg/mL conc.
1 mg40 units20 units10 units
2 mg80 units40 units20 units
4 mg160 units80 units40 units
6 mg240 units120 units60 units
8 mg320 units160 units80 units
12 mg480 units240 units120 units

How to read this: "Concentration" is how much Retatrutide is in 1 mL of reconstituted solution. 100 units = 1 mL on a standard insulin syringe. Always confirm your prescribed dose with your healthcare provider before injection.

Retatrutide Dosing Guide

Titration: start 2mg weekly for 4 wks, then titrate up 2mg every 4 wks to 8–12mg maintenance. Research-only; not FDA-approved. Track glucose, ApoB, LFTs monthly.

Blood markers to track

HbA1cFasting glucoseApoBTriglyceridesLFTsWeightHeart rate (monitor - can increase)

Note: Not FDA-approved. In Phase 3 trials under brand name Maridebart. Triple agonist - GLP-1 + GIP + glucagon. Expected FDA filing 2026. Increases heart rate ~4-6 bpm - monitor in cardiovascular patients.

WHAT TO DO NEXT

You have the dose. Now track whether it’s doing anything.

Log every Retatrutide injection alongside your HbA1cand Fasting glucose readings. Compare draws over time in your free dashboard — so the next change you make is based on your numbers, not a guess.

Start tracking Retatrutide free →

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NOT MEDICAL ADVICE. FOR INFORMATIONAL USE ONLY. CONSULT A LICENSED HEALTHCARE PROVIDER. · All Calculators · Blog · Home