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Retatrutide Reconstitution & Dosage Calculator

Triple agonist (GLP-1 / GIP / glucagon) showing ~24% mean body weight reduction at 48 weeks in Phase 2 trials — the largest weight-loss effect of any GLP-1 class compound to date.

Half-life: ~6 daysFrequency: Once weeklyRoute: Subcutaneous

Retatrutide Reconstitution Calculator

Pre-filled with standard Retatrutide values. Adjust as needed.

Typical range: 1–12mg weekly (titration)
Concentration6000 mcg/mL
Draw volume0.333 mL
Draw to (100-unit syringe)33.3 units
Total doses per vial6 doses
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Retatrutide Dosing Guide

Titration: start 2mg weekly for 4 wks, then titrate up 2mg every 4 wks to 8–12mg maintenance. Research-only; not FDA-approved. Track glucose, ApoB, LFTs monthly.

Blood markers to track

HbA1cFasting glucoseApoBTriglyceridesLFTsWeightHeart rate (monitor — can increase)

Note: Not FDA-approved. In Phase 3 trials under brand name Maridebart. Triple agonist — GLP-1 + GIP + glucagon. Expected FDA filing 2026. Increases heart rate ~4-6 bpm — monitor in cardiovascular patients.

WHAT TO DO NEXT

You have the dose. Now track whether it’s doing anything.

Log every Retatrutide injection alongside your HbA1c and Fasting glucose readings. Compare draws over time in your free dashboard — so the next change you make is based on your numbers, not a guess.

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