TB-500 Side Effects
TB-500 (a Thymosin Beta-4 fragment) is reported as generally well-tolerated, with mild and infrequent effects. As with BPC-157, human safety data is limited and individual tracking carries weight.
When they appear & how long they last
Reported effects are typically mild and early-cycle. The twice-weekly loading schedule means systemic exposure builds gradually, so any response tends to emerge over the first weeks rather than acutely.
Commonly reported TB-500 side effects
The most commonly reported effect, usually transient during loading.
Reported shortly after injection by some users.
Mild local redness or soreness.
Occasional during the loading phase.
When to contact your provider
- Injection-site infection signs (spreading redness, warmth, fever)
- Allergic-reaction signs
- Any unexpected, persistent systemic symptom
Biomarkers worth tracking on TB-500
These catch issues early - before you feel them. Pull a baseline before you start, then re-check on the cadence noted below.
How to actually track TB-500 side effects
TB-500 is most often run alongside BPC-157 (the "Wolverine Stack"), so track them as a unit: log both compounds against your recovery metric and watch hs-CRP across the cycle. The twice-weekly cadence makes a dose log genuinely useful - it is easy to lose track of a non-daily schedule without one.
Track TB-500 with MyProtocolStack →Side effects for other compounds
Frequently asked questions
What are the common side effects of TB-500?
The most commonly reported TB-500 side effects: Fatigue / lethargy, Head-rush or lightheadedness, Injection-site reaction, Temporary flu-like feeling. TB-500 (a Thymosin Beta-4 fragment) is reported as generally well-tolerated, with mild and infrequent effects. As with BPC-157, human safety data is limited and individual tracking carries weight.
When do TB-500 side effects appear and how long do they last?
Reported effects are typically mild and early-cycle. The twice-weekly loading schedule means systemic exposure builds gradually, so any response tends to emerge over the first weeks rather than acutely.
When should I contact a provider about TB-500 side effects?
Contact your provider for any of these: Injection-site infection signs (spreading redness, warmth, fever); Allergic-reaction signs; Any unexpected, persistent systemic symptom.