TRT / Hormone Support

Cofactors for endogenous testosterone production and TRT optimization.

PAIRS WITHTRTEnclomipheneHCGKisspeptin

Educational reference combinations only — not medical advice. No supplement listed is presented as a treatment for any condition. Always consult a licensed healthcare provider before starting any new protocol.

Why these pair

Zinc, magnesium, vitamin D, and boron are the four most-cited cofactors in TRT optimization research. Tongkat Ali has Phase 2 data for free-T support.

The 5 supplements

Zinc Picolinate30 mg

mineralEvening

Aromatase inhibitor at physiologic doses. Take away from copper.

Magnesium Glycinate400 mg

mineralBedtime

Lowers SHBG, increases free testosterone in deficient men.

Vitamin D35000 IU

vitaminMorning

Low D3 strongly associated with lower total T in published research.

Boron6 mg

mineralMorning

Lowers SHBG within 7 days. Cheapest free-T optimizer.

Tongkat Ali200 mg

herbMorning

Standardized to 2% eurycomanone. Cycle 8 weeks on / 4 off.

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Other supplement stacks

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Common nutrient gaps that show up after months on semaglutide or tirzepatide.

GH Peptide Support

Cofactors that improve growth-hormone pulse magnitude and IGF-1 response.

Recovery Stack

Tissue-repair cofactors that pair with healing peptides.

Longevity Foundation

The five most-researched longevity supplements at conservative doses.

Educational reference combinations. Not medical advice. Doses listed are common adult reference ranges from published research; individual needs vary significantly. Always consult a licensed healthcare provider before starting any new supplement protocol.